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It is our mission to answer this question, and important findings are being obtained in our cooperative research with Tohoku University (Ito et. al, Biosci. Biotechnol. Biochem., 89, 633-637, 2025, doi:10.1093/bbb/zbaf002).

URL    https://doi.org/10.1093/bbb/zbaf002

Specifically, we are finding that both oil-soluble and water-soluble Γ-oryzanol are indeed absorbed into the rat body, but that there is no big difference in the amount absorbed. both oil-soluble and Γ-oryzanol are absorbed into the rat body, but there is no significant difference in the amount absorbed. This result suggests that the absorption of oil-soluble substances is not uniformly improved by their water-solubilization, and that a water-solubilization technique appropriate to the characteristics of each substance is necessary.